Dartmouth Biology Research Paper

 The Biology Department offers a number of opportunities for undergraduate research. Some students pursue research only for one term, while others spend up to four years working in the same laboratory.

How Do I Find a Research Lab?  Maximilian Jentzsch ’15 talks about tools for finding a research lab and how he found a lab.

Department faculty host undergraduate researchers through campus-wide programs such as WISP and Presidential Scholars, our departmental independent study and Honors programs, and nationwide programs such as Leadership Alliance and NSF's Research Experiences for Undergraduates (REU). 

We encourage all undergraduates interested in a research experience to talk with faculty, graduate teaching assistants, and other undergraduates about what type of research experience might be most appropriate for them, and to be assertive about contacting prospective research advisors. Please keep in mind that most research laboratories sponsor a few undergraduates at a time, and so lack of a research opportunity in a particular lab at a particular time often means only that there is a lack of space. Be persistent and flexible — in our experience, most everyone who truly wants a research experience is able to find one during his/her time at Dartmouth.

COBRE Center for Lung Biology Research

Lung disease is the third most frequent cause of death in this country, claiming ~360,000 Americans annually. Tragically, an additional 25 million live with chronic lung diseases, including asthma, emphysema, cancer and cystic fibrosis. Unfortunately, the number of individuals with lung disease is increasing at an alarming rate, thus, a better understanding of the etiology of lung disease and new therapeutics to treat lung disease are required.

The goals of the Dartmouth Lung Biology Center, funded by a COBRE award by the NCRR and NIGMS since 2003 (P20-RR018787/GM103413 and P30-GM106394), and funding from the CF Research Development Program (CFRDP) are to enhance the research efforts of our faculty and students by:

  1. Integration of the COBRE supported Cores (Host Pathogen Integration Core, Live Cell Imaging Core, and Translational Research Core) with shared services in the Geisel School of Medicine at Dartmouth, Dartmouth Hitchcock Medical Center(DHMC) and other IDeA supported Cores, including Bioinformatics and Biostatistics;

  2. Fostering synergistic scientific collaboration through the COBRE Research Projects, associated Cores, and other basic and translational infrastructure and programs at the Geisel School of Medicine at Dartmouth/DHMC, including the Immunology COBRE, the Bioinformatics COBRE, the Center for Epidemiology COBRE, and the Dartmouth INBRE programs;

  3. Mentoring and supporting the career development of all faculty in the program, and;

  4. Providing administrative support.

Pilot Projects:

Microbial Activity as a Determinant of Health Status in Cystic Fibrosis

Project Leader: Alex H. Gifford, M.D.

Promoting the Phagocytic Clearance of Non-Motile P. Aeruginosa

Project Leader: Brent Berwin, Ph.D.
Co-Investigator: Scott Gerber, Ph.D.

A Novel Murine Model of Allergic Bronchopulmonary Aspergillosis

Project Leader: Robert A. Cramer, Ph.D.
Co-Investigator: Joshua J. Obar, Ph.D.

Evolution of P. Aeruginosa Biofilm Hyper-Production in Light of Local Fluid Viscosity and Multispecies Interactions within the CF Lung

Project Leader: Carey Nadell, Ph.D.

Impact of CF Therapies on the Pathogenesis of Aspergillus Fumigatus

Project Leader: Robert A. Cramer, Ph.D.
Collaborating Faculty: Alex H. Gifford, M.D.

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